PATHOLOGY

Detailed explanation-1: -Atherosclerosis is a thickening or hardening of the arteries. It is caused by a buildup of plaque in the inner lining of your artery. Plaque is made up of deposits of fatty substances, cholesterol, cellular waste products, calcium and fibrin. Your affected artery walls thicken and lose elasticity.

Detailed explanation-2: -Atherosclerosis occurs when your arteries become clogged with fatty deposits (plaque), causing them to lose their elasticity and become narrower. Plaque is a sticky mixture of fatty streaks that build up, making the walls of the arteries thick and hard. Over time, the artery narrows or gets blocked.

Detailed explanation-3: -Arteriosclerosis is defined as a proliferative and/or degenerative (hyaline) change to the tunica media and tunica intima of arteries that results in loss of elasticity ("hardening") and is often associated with luminal narrowing.