PATHOLOGY

Detailed explanation-1: -Paracrine signalling is when signal molecules are secreted into the extracellular fluid by signalling cells and the secreted molecules only affect neighbouring cells surrounding the signalling cell, acting as local mediators. Usually the signalling and target cells in paracrine signalling are of different cell types.

Detailed explanation-2: -Cells that produce paracrine factors secrete them into the immediate extracellular environment.

Detailed explanation-3: -A system called “paracrine signaling” allows cells to communicate with each other by releasing signaling molecules that bind to and activate surrounding cells.

Detailed explanation-4: -Examples of paracrine signaling include responses to allergens, tissue repair, the formation of scar tissue, and blood clotting.