PATHOLOGY

Detailed explanation-1: -Intercellular communication is largely mediated by gap junctions (GJs), a type of specialized membrane contact composed of variable number of channels that enable direct communication between cells by allowing small molecules to pass directly into the cytoplasm of neighbouring cells.

Detailed explanation-2: -Gap junctions are clusters of intercellular channels that allow direct diffusion of ions and small molecules between adjacent cells.

Detailed explanation-3: -Gap junctions (GJ) provide intercellular communication in all multicellular animal species, being as evolutionary distant as worm and men. In the traditional view GJs are known as specialized cell junctions forming communicating channels connecting the cytoplasm of adjacent cells.

Detailed explanation-4: -Direct Signaling Across Gap Junctions Gap junctions in animals and plasmodesmata in plants are connections between the plasma membranes of neighboring cells. These water-filled channels allow small signaling molecules, called intracellular mediators, to diffuse between the two cells.

Detailed explanation-5: -Tight junctions facilitate the cells to communicate with each other.