PATHOLOGY

Detailed explanation-1: -Diabetes occurs when the control mechanism for insulin becomes imbalanced, either because there is a deficiency of insulin or because cells have become resistant to insulin.

Detailed explanation-2: -Insulin is a key player in developing type 2 diabetes. This vital hormone-you can’t survive without it-regulates blood sugar (glucose) in the body, a very complicated process. Here are the high points: The food you eat is broken down into blood sugar.

Detailed explanation-3: -Type 1 diabetes is an auto-immune disease that results in the destruction of -cells in the pancreas1. With the destruction of -cells, the body cannot produce enough insulin to maintain energy homeostasis.

Detailed explanation-4: -Through its various hormones, particularly glucagon and insulin, the pancreas maintains blood glucose levels within a very narrow range of 4–6 mM. This preservation is accomplished by the opposing and balanced actions of glucagon and insulin, referred to as glucose homeostasis.