PATHOLOGY

Detailed explanation-1: -If blood glucose is high, then no glucagon is secreted. When blood glucose goes low, however (such as between meals, and during exercise), more and more glucagon is secreted. Like insulin, glucagon has an effect on many cells of the body, but most notably the liver.

Detailed explanation-2: -Pancreatic Hormones: Insulin and Glucagon Glucagon secretion is stimulated by a fall in the blood glucose level or a rise in the blood levels of free fatty acids or certain amino acids (see Table 7-8). Most of the biological consequences of glucagon lead to an increase in the blood level of glucose.

Detailed explanation-3: -If you have too much glucagon, your cells don’t store sugar, and instead, sugar stays in your bloodstream. Glucagonoma leads to diabetes-like symptoms and other severe symptoms, including: high blood sugar. excessive thirst and hunger due to high blood sugar.