PATHOLOGY

Detailed explanation-1: -Lipid-derived hormones are structurally similar to cholesterol and include steroid hormones such as estradiol and testosterone. Amino acid-derived hormones are relatively small molecules and include the adrenal hormones epinephrine and norepinephrine.

Detailed explanation-2: -Lipid-soluble hormones easily diffuse through the cell membrane. Steroid hormones are the most common circulating lipid-soluble hormones. Steroid hormones include: testosterone, estrogens, progesterone, aldosterone and cortisol.

Detailed explanation-3: -The main class of lipid-derived hormone is the steroids which are derived from cholesterol and the eicosanoids. Steroid hormones include testosterone, estrogen and cortisol.

Detailed explanation-4: -Steroidogenic enzymes are responsible for the biosynthesis of cholesterol from various steroid hormones including corticoids, progestins, androgens and estrogens. These are generally synthesized in the adrenal cortex, gonads (testes and ovaries), brain, placenta and adipose tissue (Falkenstein et al.