PATHOLOGY

Detailed explanation-1: -Insulin has an effect on a number of cells, including muscle, red blood, and fat. In response to insulin, these cells absorb glucose out of the blood, having the net effect of lowering the high blood glucose levels into the normal range.

Detailed explanation-2: -Insulin causes glucose to deposited in the liver as glycogen; then, during the next few hours, when blood glucose concentration falls, the liver releases glucose back into the blood, decreasing fluctuations. Clinical significance: During severe liver disease, it is impossible to maintain blood glucose concentration.

Detailed explanation-3: -A well-known effect of insulin is to decrease the concentration of glucose in blood, which should make sense considering the mechanisms described above. Another important consideration is that, as blood glucose concentrations fall, insulin secretion ceases.

Detailed explanation-4: -This rise in blood glucose causes insulin to be released from the pancreas so glucose can move inside the cells and be used. As glucose moves inside the cells, the amount of glucose in the bloodstream returns to normal and insulin release slows down.