PATHOLOGY

Detailed explanation-1: -In myasthenia gravis, the immune system damages the communication system between the nerves and muscles, making the muscles weak and easily tired. It’s not clear why this happens, but it’s been linked to issues with the thymus gland (a gland in the chest that’s part of the immune system).

Detailed explanation-2: -In many adults with myasthenia gravis, the thymus gland remains large. People with the disease typically have clusters of immune cells in their thymus gland and may develop thymomas (tumors of the thymus gland). Thymomas are most often harmless, but they can become cancerous.

Detailed explanation-3: -Myasthenia gravis (MG) is an autoimmune disease caused by the action of specific antibodies to the postsynaptic membrane of the neuromuscular junction, leading to impaired neuromuscular transmission. Patients with MG have an increased incidence of other autoimmune diseases.

Detailed explanation-4: -The thymus gland, a part of your immune system situated in the upper chest beneath the breastbone, may trigger or maintain the production of antibodies that result in the muscle weakness.

Detailed explanation-5: -Thymic hyperplasia is often accompanied by autoimmune diseases such as systemic lupus erythematosus, myasthenia gravis and rheumatoid arthritis. While the case who suffered from thymic hyperplasia combined with primary Sjogren’s syndrome have rarely been reported (1, 2).