PATHOLOGY

Detailed explanation-1: -Steroid hormones are insoluble in water; they are carried by transport proteins in blood. As a result, they remain in circulation longer than peptide hormones.

Detailed explanation-2: -All three steroids have low water solubility, which increases considerably at sonication for testosterone and estradiol-17 beta. The phosphatidylcholine vesicles have a very small solubilising capacity for the steroids; about 20 mumol/mol.

Detailed explanation-3: -Steroid hormones are insoluble in water, and they are transported by transport proteins in blood.

Detailed explanation-4: -Like cholesterol, steroid hormones are not soluble in water (they are hydrophobic). Because blood is water-based, lipid-derived hormones must travel to their target cell bound to a transport protein.