PATHOLOGY

Detailed explanation-1: -Your pineal gland releases the highest levels of melatonin when there’s darkness and decreases melatonin production when you’re exposed to light. In other words, you have low levels of melatonin in your blood during the daylight hours and peak levels of melatonin during the nighttime.

Detailed explanation-2: -Melatonin may have an antidepressant effect by increasing the expression of GABAA receptors in the rat brain. Melatonin also increases neuroplasticity in the hippocampus, which plays an important role in the development of depression.

Detailed explanation-3: -It doesn’t make you sleep, but as melatonin levels rise in the evening it puts you into a state of quiet wakefulness that helps promote sleep, ‘’ explains Johns Hopkins sleep expert Luis F. Buenaver, Ph.D., C.B.S.M. “Most people’s bodies produce enough melatonin for sleep on their own.