PATHOLOGY

Detailed explanation-1: -Melatonin is the only known hormone synthesized by the pineal gland and is released in response to darkness hence the name, “hormone of darkness” [10]. Melatonin provides a circadian and seasonal signal to the organisms in vertebrates.

Detailed explanation-2: -It’s a part of your endocrine system and secretes the hormone melatonin. Your pineal gland’s main job is to help control the circadian cycle of sleep and wakefulness by secreting melatonin.

Detailed explanation-3: -The main function of the pineal gland is to receive and convey information about the current light-dark cycle from the environment via the production and secretion of melatonin cyclically at night (dark period) (6, 7).

Detailed explanation-4: -Pineal Gland Essentials Located deep in the center of the brain, the pineal gland was once known as the “third eye.” The pineal gland produces melatonin, which helps maintain circadian rhythm and regulate reproductive hormones.

Detailed explanation-5: -Melatonin, mostly released by the pineal gland, is a circadian rhythm-regulated and multifunctional hormone. Great advances in melatonin research have been made, including its role in rhythms of the sleep-wake cycle, retardation of ageing processes, as well as antioxidant or anti-inflammatory functions.