PATHOLOGY

Detailed explanation-1: -A goiter is an enlargement of the thyroid, the H-shaped gland that wraps around the front of your windpipe, just below your Adam’s apple. A goiter can be smooth and uniformly enlarged, called diffuse goiter, or it can be caused by one or more nodules within the gland, called nodular goiter .

Detailed explanation-2: -Enlarged thyroid A goiter may be an overall enlargement of the thyroid, or it may be the result of irregular cell growth that forms one or more lumps (nodules) in the thyroid. A goiter may be associated with no change in thyroid function or with an increase or decrease in thyroid hormones.

Detailed explanation-3: -Simple (diffuse) goiter: This type of goiter happens when your entire thyroid gland swells and feels smooth to the touch. Nodular goiter: This type of goiter happens when a solid or fluid-filled lump called a nodule develops within your thyroid and makes it feel lumpy.

Detailed explanation-4: -Diffuse toxic goiter is an autoimmune condition characterized by a diffusely hyperplastic thyroid gland with excessive overproduction of thyroid hormone. Graves disease, the most common cause of hyperthyroidism, is characterized by the stigmata of diffuse toxic goiter, oculopathy, and pretibial myxedema/acropachy.

Detailed explanation-5: -Graves’ disease (German: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism.