PATHOLOGY

Detailed explanation-1: -Negative feedback mechanism normalizes the things when they start becoming too extreme. For eg., the thyroid gland is regulated by a negative feedback mechanism. The hormone secreted by the hypothalamus stimulates the pituitary gland to release thyroid stimulating hormone.

Detailed explanation-2: -Negative feedback keeps the concentration of a hormone within a relatively narrow range and maintains homeostasis. Very few endocrine hormones are regulated by positive feedback loops. Positive feedback causes the concentration of a hormone to become increasingly higher.

Detailed explanation-3: -…a prime example of a negative feedback control system. The production and secretion of thyroxine and triiodothyronine by the thyroid gland are stimulated by the hypothalamic hormone thyrotropin-releasing hormone and the anterior pituitary hormone thyrotropin.