PATHOLOGY

Detailed explanation-1: -In a negative feedback mechanism, high levels of a hormone turn off further release of that hormone. This usually occurs in a stepwise pattern: the high concentration of the hormone signals back through the system to turn off production of the hormone or hormones that stimulated its release.

Detailed explanation-2: -The type of signal used in a heating system is called negative feedback because the system is turned off by the condition it produces.

Detailed explanation-3: -Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.

Detailed explanation-4: -Thus, failure of the negative feedback mechanism can result in high blood glucose levels, which have a variety of negative health effects. Let’s take a closer look at diabetes. In particular, we will discuss diabetes type 1 and type 2. Diabetes can be caused by too little insulin, resistance to insulin, or both.

Detailed explanation-5: -Another example of negative feedback is the regulation of the blood calcium level. The parathyroid glands secrete parathyroid hormone, which regulates the level of calcium in the blood. If calcium decreases, the parathyroid glands sense the decrease and secrete more parathyroid hormone.