PATHOLOGY

Detailed explanation-1: -Moreover, glucocorticoids modulate the function of pancreatic and cells to regulate the secretion of glucagon and insulin, two hormones that play a pivotal role in the regulation of blood glucose levels.

Detailed explanation-2: -Glucocorticoids also induce insulin resistance, hyperglycemia, and hyperlipidemia.

Detailed explanation-3: -The effect of glucocorticoids on glucose metabolism is likely the result of impairment of multiple pathways including beta cell dysfunction (sensitivity to glucose and ability to release insulin) and insulin resistance in other tissue.