PATHOLOGY

Detailed explanation-1: -Prostaglandin is a non-steroidal hormone while estradiol, estrone, and progestrone are all steroidal hormones.

Detailed explanation-2: -Steroids and prostaglandins are both classes of lipid hormones. However, they differ fundamentally in their molecular substrates, synthetic pathways, cellular receptors, mechanisms and speed of action, and physiological responses.

Detailed explanation-3: -Thyroxine is a derivative of the the amino acid tyrosine bound covalently to iodine. It is not a steroid hormone.

Detailed explanation-4: -There are four major classes of steroid hormones: progestins, androgens, estrogens, and corticoids, which contain 21, 19, 18, and 21 carbons, respectively. Steroid hormones are synthesized by dehydrogenases and cytochrome P450 enzymes, which catalyze hydro-xylation and dehydroxylation-oxidation reactions.

Detailed explanation-5: -The steroids that are made almost exclusively in the adrenal glands are cortisol, 11-deoxycortisol, aldosterone, corticosterone, and 11-deoxycorti-costerone. Most other steroid hormones, including the estrogens, are made by the adrenal glands and the gonads [1].