PATHOLOGY

PATHOLOGY MCQ

ENDOCRINE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which statement describes a feedback mechanism involving the human pancreas?
A
The production of estrogen stimulates the formation of gametes for sexual reproduction.
B
The level of oxygen in the blood is related to heart rate.
C
The level of sugar in the blood is affected by the amount of insulin in the blood.
D
The production of urine allows for excretion of cell waste.
Explanation: 

Detailed explanation-1: -The control of blood sugar (glucose) by insulin is a good example of a negative feedback mechanism. When blood sugar rises, receptors in the body sense a change. In turn, the control center (pancreas) secretes insulin into the blood effectively lowering blood sugar levels.

Detailed explanation-2: -Negative feedback When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose. Some is stored as body fat and other is stored as glycogen in the liver and muscles. If the blood glucose level is too low, the pancreas releases the hormone glucagon.

Detailed explanation-3: -Thus, insulin and glucagon actions on blood glucose levels mediate two negative feedback loops in which insulin acts as a repressor, while glucagon as activator (Fig. 1b). Failure of beta cells to secrete insulin in diabetic patients results in uncontrolled fluctuations in blood glucose levels.

Detailed explanation-4: -In a negative feedback loop, feedback serves to reduce an excessive response and keep a variable within the normal range . Two processes controlled by negative feedback are body temperature regulation and control of blood glucose.

There is 1 question to complete.