PATHOLOGY

Detailed explanation-1: -Increased growth hormone production from the pituitary gland-as a results of sex hormones-leads to the pubertal growth spurt. The adrenal glands (two small glands located above the kidneys) also play a role in producing sex steroids (adrenarche).

Detailed explanation-2: -Puberty begins when the gonadotropin-releasing hormone (GnRH) neurons of the hypothalamus secrete GnRH in a pulsatile manner. Pulsatile GnRH causes pituitary gonadotrophs to synthesize and release luteinizing hormone (LH) and follicle-stimulating hor-mone (FSH).

Detailed explanation-3: -The glands and organs that make hormones and release them directly into the blood so they can travel to tissues and organs all over the body. The hormones released by the endocrine system control many important functions in the body, including growth and development, metabolism, and reproduction.

Detailed explanation-4: -Thymus. Located in the upper torso, the thymus is active until puberty and produces hormones that are important for the development of a type of white blood cell called a T cell.