PATHOLOGY

Detailed explanation-1: -Fertilization usually takes place in a fallopian tube that links an ovary to the uterus. If the fertilized egg successfully travels down the fallopian tube and implants in the uterus, an embryo starts growing.

Detailed explanation-2: -Contact Between Sperm and Oocyte. Upon ovulation, the oocyte released by the ovary is swept into-and along-the uterine tube. Fertilization must occur in the distal uterine tube because an unfertilized oocyte cannot survive the 72-hour journey to the uterus.

Detailed explanation-3: -Fertilization occurs at ampulla isthamus junction due to paracrine signalling from tryosine kinase and lactoferrin which is instrumental in combining sperm with ovum.