PATHOLOGY

Detailed explanation-1: -These latter cells, called the primary oocytes, progress through the first meiotic prophase until the diplotene stage, at which point they are maintained until puberty.

Detailed explanation-2: -The primary oocytes (2n) in female ovaries begin their meiosis in the fetal stage but become arrested in prophase I of meiosis I. When a female hits puberty these arrested primary oocytes (2n) completes meiosis I to form large secondary oocyte (n) and small first polar body(n). Meiosis I is followed by meiosis II.

Detailed explanation-3: -Oocytes are arrested at the first meiotic prophase, held in meiotic arrest by the surrounding follicle cells until a surge of LH from the pituitary stimulates the immature oocyte to resume meiosis. Meiotic arrest depends on a high level of cAMP within the oocyte.