PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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synthesis of ATP
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replication of DNA
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formation of peptide bonds
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pairing of chromosomes in meiosis
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Detailed explanation-1: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).
Detailed explanation-2: -Complementary base pairing is the phenomenon where in DNA guanine always hydrogen bonds to cytosine and adenine always binds to thymine. The bond between guanine and cytosine shares three hydrogen bonds compared to the A-T bond which always shares two hydrogen bonds.
Detailed explanation-3: -This process is known as DNA replication. During DNA replication, the two strands of DNA separate. These separated strands act as a template on which a new strand of DNA is synthesized through complementary base pairing. Thus, the two strands of DNA molecule are complementary to each other.
Detailed explanation-4: -During DNA replication, each of the two strands that make up the double helix serves as a template from which new strands are copied. The new strand will be complementary to the parental or “old” strand. Each new double strand consists of one parental strand and one new daughter strand.