PATHOLOGY

Detailed explanation-1: -Question: A carrier of a genetic disorder who does not show symptoms is most likely to be to transmit it to offspring.

Detailed explanation-2: -In autosomal recessive inheritance, variants occur in both copies of the gene in each cell. The parents of an individual with an autosomal recessive condition each carry one copy of the altered gene, but they typically do not show signs and symptoms of the condition.

Detailed explanation-3: -A carrier, as related to genetics, is an individual who “carries” and can pass on to its offspring a genomic variant (allele) associated with a disease (or trait) that is inherited in an autosomal recessive or sex-linked manner, and who does not show symptoms of that disease (or features of that trait).

Detailed explanation-4: -Does a genetic carrier have symptoms? The traditional view has been that a genetic carrier will not exhibit symptoms of the disorder. However, the scientific understanding of genetic disorders has since evolved to show that carriers may go on to develop physical symptoms.