PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Gene therapy
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Sex-linked trait
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Polygenic
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Pedigree
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Detailed explanation-1: -A polygenic trait is a characteristic, such as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the patterns of Mendelian inheritance . Many polygenic traits are also influenced by the environment and are called multifactorial.
Detailed explanation-2: -phenotype, all the observable characteristics of an organism that result from the interaction of its genotype (total genetic inheritance) with the environment.
Detailed explanation-3: -In polygenic inheritance, traits are determined by multiple genes, or polygenes. Polygenic traits may express several different phenotypes, or displayed characteristics. Polygenic inheritance is a type of incomplete dominance inheritance, where the expressed phenotypes are a mixture of inherited traits.
Detailed explanation-4: -In humans, height, skin color, hair color, and eye color are examples of polygenic traits. Type-2 diabetes, coronary heart disease, cancer, and arthritis are also deemed polygenic.
Detailed explanation-5: -Polygenic trait: also called quantitative or complex trait, a polygenic trait is determined by several genes and/or regulatory loci.