PATHOLOGY

Detailed explanation-1: -The term albinism usually refers to oculocutaneous (ok-u-low-ku-TAY-nee-us) albinism (OCA). OCA is a group of disorders passed down in families where the body makes little or none of a substance called melanin. The type and amount of melanin in your body determines the color of your skin, hair and eyes.

Detailed explanation-2: -Albinism affects the production of melanin, the pigment that colours skin, hair and eyes. It’s a lifelong condition, but it does not get worse over time. People with albinism have a reduced amount of melanin, or no melanin at all. This can affect their colouring and their eyesight.

Detailed explanation-3: -The disorder can be divided into two groups: oculocutaneous albinism (OCA)–the most common condition among hypopigmentation disorders–with varying degrees of involvement of the eyes, hair, and skin; the second group is the less common group called ocular albinism (OA) with disease involvement limited to the eyes.

Detailed explanation-4: -Albinism is a rare genetic condition caused by mutations of certain genes that affect the amount of melanin your body produces. Melanin controls the pigmentation (color) of your skin, eyes and hair. People with albinism have extremely pale skin, eyes and hair.

Detailed explanation-5: -oculocutaneous albinism (OCA) ocular albinism. Hermansky-Pudlak syndrome. Chediak-Higashi syndrome. Griscelli syndrome. 22-Sept-2021