PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A man with type O blood has children with a woman who is heterozygous to type A blood. What is the probability that their children will have type A blood?
A
0%
B
25%
C
50%
D
100%
Explanation: 

Detailed explanation-1: -Answer and Explanation: No, a woman with blood type A cannot produce a child with blood type O if the father has the AB blood type. This is because the ABO blood group is the product of two alleles, one from the mother and one from the father.

Detailed explanation-2: -We know that she is homozygous. The father could be homozygous with two alleles of type A or he may be heterozygous with one allele of type A and one allele of type O. If the father is heterozygous, there is a 50% probability for a blood type A child and a 50% probability for a blood type O child.

Detailed explanation-3: -A mother who is blood type O can only pass an O allele to her son or daughter. A father who is blood type AB could pass either an A or a B allele to his son or daughter. This couple could have children of either blood type A (O from mother and A from father) or blood type B (O from mother and B from father).

Detailed explanation-4: -If the man has a blood type B with the genotype BB cross with a woman that has a genotype AO, the genotypic ratio for the offspring is 2 AB: 2 BO. It means that 50% of the children will have the blood type AB (genotype AB ) and 50% of the children will have the blood type B (genotype BO).

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