PATHOLOGY

Detailed explanation-1: -If the gene is faulty, the result is hemophilia unless there is a dominant, normal gene on a matching X chromosome. Hemophilia is a sex-linked recessive disorder. These kinds of defects occur more often in men than in women.

Detailed explanation-2: -Although it is rarer for women to have hemophilia when compared to men, women can also have the condition. It is important to raise awareness about this fact to help women with hemophilia receive the care and support they need to live healthy lives.

Detailed explanation-3: -As hemophilia is an X-linked disease, it is more common in males as they have only one X-chromosome, and a defect in one copy of the gene is sufficient to cause the disease.

Detailed explanation-4: -Frequency. The two major forms of hemophilia occur much more commonly in males than in females. Hemophilia A is the most common type of the condition; 1 in 4, 000 to 1 in 5, 000 males worldwide are born with this disorder. Hemophilia B occurs in approximately 1 in 20, 000 newborn males worldwide.