PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Colorblindness is a recessive x-linked disorder. Which genotype represents a female who is colorblind?
A
XNXn
B
XnXn
C
XNXN
D
XnY
Explanation: 

Detailed explanation-1: -The genotype of a woman who is colour blind is XcXc. This is because she colour blind, and carries two X-linked colour vision allele.

Detailed explanation-2: -Examples of X-linked recessive conditions include red-green color blindness and hemophilia A: Red-green color blindness. Red-green color blindness means that a person cannot see shades of red and green (usually blue-green).

Detailed explanation-3: -Males have 1 X chromosome and 1 Y chromosome, and females have 2 X chromosomes. The genes that can give you red-green color blindness are passed down on the X chromosome. Since it’s passed down on the X chromosome, red-green color blindness is more common in men.

Detailed explanation-4: -X-linked recessive inheritance refers to genetic conditions associated with mutations in genes on the X chromosome. A male carrying such a mutation will be affected, because he carries only one X chromosome. A female carrying a mutation in one gene, with a normal gene on the other X chromosome, is generally unaffected.

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