PATHOLOGY MCQ
GENETICS AND DISEASE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Daughters may or may not carry the disorder, and sons may or may not have the disorder
|
|
|
Daughters and sons may both be carriers of the disorder and sons may also have the disorder
|
|
|
Daughters will always be carriers of the disorder and sons will always have the disorder
|
|
|
Daughters may or may not have the disorder and sons may or may not carry the disorder
|
Detailed explanation-1: -Fragile X syndrome is a genetic disorder caused by a change to one of the genes on the X chromosome. It is the most common inherited cause of intellectual disability. Fragile X syndrome is also linked to features of autism spectrum disorder.
Detailed explanation-2: -FXS affects both males and females. Females often have milder symptoms than males. The exact number of people who have FXS is unknown, but a review of research studies estimated that about 1 in 7, 000 males and about 1 in 11, 000 females have been diagnosed with FXS.
Detailed explanation-3: -X-linked dominant disorders such as fragile X syndrome are caused by an abnormal gene located on the X chromosome. Females with the abnormal gene may be affected by this disorder. Males are usually more severely affected than females).
Detailed explanation-4: -Fragile X syndrome, also termed Martin-Bell syndrome or marker X syndrome, is the most common cause of inherited mental retardation, intellectual disability, and autism and is the second most common cause of genetically associated mental deficiencies, after trisomy 21.