PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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100%
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0%
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50%
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75%
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Detailed explanation-1: -The “no freckles” allele (f) is recessive, which means that a person must inherit two copies of the f allele (one from each parent) in order to not have freckles. If the alleged father is homozygous dominant (FF) and the mother is heterozygous (Ff), the child will have freckles (Ff).
Detailed explanation-2: -Freckles are associated with a variant of a gene called MC1R. MC1R alerts the body when exposed to harmful UV radiation is taking place. This is a dominant gene, meaning anyone with at least one copy of the freckle variant from either parent will have freckles.
Detailed explanation-3: -Freckles are dominant (F) and primarily controlled by the MC1R gene. A person that is heterozygous for freckles would have a phenotype that shows freckles on their skin and possess the genotype Ff.