PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Height in humans is determined by the interaction of many alleles. This is an example of
A
Mendelian inheritance
B
codominance
C
polygenic inheritance
D
incomplete dominance
Explanation: 

Detailed explanation-1: -A polygenic trait is a characteristic, such as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the patterns of Mendelian inheritance . Many polygenic traits are also influenced by the environment and are called multifactorial.

Detailed explanation-2: -Height is a polygenic trait which is controlled by at least three genes with six alleles. Polygenic inheritance shows continuous variation. There is no distinct alternative like tall and short, rather there is a whole range of possible heights.

Detailed explanation-3: -Polygenic traits have many possible phenotypes (physical characteristics) that are determined by interactions among several alleles. Examples of polygenic inheritance in humans include traits such as skin color, eye color, hair color, body shape, height, and weight.

Detailed explanation-4: -A complex inheritance pattern. How, then, is height inherited? Height and other similar features are controlled not just by one gene, but rather, by multiple (often many) genes that each make a small contribution to the overall outcome. This inheritance pattern is sometimes called polygenic inheritance (poly-= many).

Detailed explanation-5: -A polygenic inheritance in human beings is skin colour. Polygenic or quantitative inheritance occurs when several genes occupying different loci on the same homologous pairs of chromosomes govern one trait. Inheritance of colour in human beings is an example of polygenic inheritance.

There is 1 question to complete.