PATHOLOGY

Detailed explanation-1: -Some people think a person with hemophilia can bleed to death from a small cut. This is not true. Usually small cuts and scrapes stop bleeding just fine. A person with hemophilia has problems when a fibrin clot is needed to stop the bleeding.

Detailed explanation-2: -Causes. Hemophilia is caused by a mutation or change, in one of the genes, that provides instructions for making the clotting factor proteins needed to form a blood clot. This change or mutation can prevent the clotting protein from working properly or to be missing altogether.

Detailed explanation-3: -Hemophilia A is a hereditary bleeding disorder caused by a lack of blood clotting factor VIII. Without enough factor VIII, the blood cannot clot properly to control bleeding.

Detailed explanation-4: -The main symptom of hemophilia is bleeding. Mild cases may not be detected until later in life, after excessive bleeding following surgery or an injury. In the worst cases, bleeding occurs for no reason. Internal bleeding may occur anywhere and bleeding into joints is common.