PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Gg
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ff
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DD
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Hh
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Detailed explanation-1: -Despite its actual genetic complexity, the inheritance of this trait usually can be predicted by a simple conceptual model in which there are two alleles, D and d. Individuals who are homozygous dominant (DD) or heterozygous (Dd) are Rh+.
Detailed explanation-2: -Homozygous means that the organism has two copies of the same allele for a gene. An organism can be homozygous dominant, if it carries two copies of the same dominant allele, or homozygous recessive, if it carries two copies of the same recessive allele.
Detailed explanation-3: -Homozygote-an individual which contains only one allele at the allelic pair; for example DD is homozygous dominant and dd is homozygous recessive; pure lines are homozygous for the gene of interest.
Detailed explanation-4: -Background: The DD genotype gene is a linkage marker for an etiologic mutation at or near the angiotensin-converting enzyme gene and has been associated with increased risk for the development of coronary artery disease, left ventricular hypertrophy and left ventricular dilation after myocardial infarction.
Detailed explanation-5: -dd = dwarf (homozygous recessive) Mendel was smart to use peas, most stocks are completely true-breeding = homozygous.