PATHOLOGY

Detailed explanation-1: -Replacing the defective genes may help treat certain diseases. For instance, a gene called p53 normally prevents tumor growth. Several types of cancer have been linked to problems with the p53 gene. If doctors could replace the defective p53 gene, that might trigger the cancer cells to die.

Detailed explanation-2: -In the future, genetic therapies may be used to prevent, treat, or cure certain inherited disorders, such as cystic fibrosis, alpha-1 antitrypsin deficiency, hemophilia, beta thalassemia, and sickle cell disease. They also may be used to treat cancers or infections, including HIV.

Detailed explanation-3: -Gene therapies can work by several mechanisms: Replacing a disease-causing gene with a healthy copy of the gene. Inactivating a disease-causing gene that is not functioning properly. Introducing a new or modified gene into the body to help treat a disease.

Detailed explanation-4: -Hope for the Future An estimated 4, 000 medical conditions are a result of gene disorders. If some of these genetic problems can be corrected through gene replacement or manipulation, individuals suffering from these diseases may enjoy longer, healthier lives, free of symptoms and the associated medical expenses.

Detailed explanation-5: -Gene therapy is a cutting edge medical treatment that has pros and cons. Gene therapy can be life-saving for some people with specific medical conditions, but it’s expensive and can cause side effects. The development of gene therapy is highly regulated by the FDA and National Institute of Health.