PATHOLOGY

Detailed explanation-1: -X-linked recessive conditions most often occur in males. X-linked recessive inheritance is a way a genetic trait or condition can be passed down from parent to child through mutations (changes) in a gene on the X chromosome.

Detailed explanation-2: -Recessive X-linked traits appear more often in males than females because, if a male receives a “bad” allele from his mother, he has no chance of getting a “good” allele from his father (who provides a Y) to hide the bad one.

Detailed explanation-3: -X-linked recessive diseases most often occur in males. Males have only one X chromosome. A single recessive gene on that X chromosome will cause the disease. The Y chromosome is the other half of the XY gene pair in the male.

Detailed explanation-4: -X-linked recessive inheritance refers to genetic conditions associated with mutations in genes on the X chromosome. A male carrying such a mutation will be affected, because he carries only one X chromosome. A female carrying a mutation in one gene, with a normal gene on the other X chromosome, is generally unaffected.

Detailed explanation-5: -Patterns of inheritance This means that males affected by an X-linked recessive disorder inherited the responsible X chromosome from their mothers. Second, X-linked recessive traits are more commonly expressed in males than females.