PATHOLOGY

Detailed explanation-1: -Each child of a parent with HD has a 50 percent chance of inheriting the HD gene. A child who does not inherit the HD gene will not develop the disease, and generally, they cannot pass it on to their children or other future generations.

Detailed explanation-2: -Both men and women can get it. If a parent has the Huntington’s disease gene, there’s a: 1 in 2 (50%) chance of each of their children developing the condition – affected children are also able to pass the gene to any children they have.

Detailed explanation-3: -There have been reports that juvenile onset Huntington’s chorea is almost always inherited from the father, and that late-onset Huntington’s chorea is inherited more often from the mother than from the father.

Detailed explanation-4: -Although anyone can develop HD, it tends to run in people of European descent (having family members who came from Europe). But the main factor is whether you have a parent with HD. If you do, you have a 50% chance of also having the disease.

Detailed explanation-5: -This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. An affected person usually inherits the altered gene from one affected parent.