PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In cocker spaniels the allele for a black coat color (B) is dominant over the allele for a brown coat color (b). If a brown cocker spaniel is crossed with a heterozygous black cocker spaniel, which of the following genotypic ratios can be expected?
A
0 BB:2 Bb:2bb
B
1 BB:2 Bb:1 bb
C
2 BB:0 Bb:2 bb
D
2 BB:1 Bb:0 bb
Explanation: 

Detailed explanation-1: -In cocker spaniels the allele for a black coat color (B) is dominant over the allele for a brown coat color (b). If a brown cocker spaniel (bb) is crossed with a heterozygous black cocker spaniel (Bb), how many of the offspring may be brown (bb)? All offspring will have short-haired fur.

Detailed explanation-2: -In cocker spaniels, black coat color (B) is dominant over red (b), and solid color (S) is dominant over spotted (s).

Detailed explanation-3: -Dogs with B/b genotype are expected to express undiluted black pigment and are carriers of brown. They will transmit the brown allele to 50% of their offspring.

Detailed explanation-4: -Finally, the genotype of an organism with two recessive alleles is called homozygous recessive. In the eye color example, this genotype is written bb.

Detailed explanation-5: -Normal fruit flies have brownish-yellow bodies, and this body color is dominant. A mutation in the gene for body color can produce flies with an ebony body color. A homozygous normal fruit fly (e+e+) is crossed with a homozygous ebony fruit fly (ee).

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