PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In fruit flies, a specific gene mutation causes the wings to become malformed. These wings are called vestigial because they do not function properly. The mutated allele for vestigial wings (v) is recessive to the allele for functioning wings (V). Two fruit flies that are heterozygous for wing shape are crossed, resulting in many offspring.Which of the following would most likely describe the population of offspring?
A
All of the offspring population have functioning wings.
B
The majority of the offspring population has functioning wings.
C
About half of the offspring population has functioning wings, and the other half of the population has vestigial wings.
D
The majority of the offspring population has vestigial wings.
Explanation: 

Detailed explanation-1: -In fruit flies, the dominant V allele produces long wings, whereas the recessive v allele produces vestigial wings.

Detailed explanation-2: -The Drosophila vestigial gene is required for proliferation and differentiation of the adult wing and for differentiation of larval and adult muscle identity. Vestigial is part of a multi-protein transcription factor complex, which includes Scalloped, a TEAD-class DNA binding protein.

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