PATHOLOGY

Detailed explanation-1: -A pedigree, as related to genetics, is a chart that diagrams the inheritance of a trait or health condition through generations of a family.

Detailed explanation-2: -A pedigree can be used to determine disease inheritance patterns within a family. Standard pedigree nomenclature. Common symbols are used to draw a pedigree (family tree). A pedigree shows relationships between family members and patterns of inheritance for certain traits and diseases.

Detailed explanation-3: -Pedigrees are used primarily by genetic counselors when helping couples decide to have children when there is evidence of a genetically inherited disorder in one or both families. They are also used when trying to determine the predisposition of someone to carry a hereditary disease for example, familial breast cancer.

Detailed explanation-4: -The three-generation pedigree provides a pictorial representation of diseases within a family and is the most efficient way to assess hereditary influences on disease.