PATHOLOGY

Detailed explanation-1: -Abstract. Somatic gene therapy involves the introduction of novel genetic material into somatic cells to express therapeutic gene products. This emerging technology holds great promise for the treatment of both inherited and acquired diseases.

Detailed explanation-2: -Somatic cell gene therapy is when therapeutic genes are transferred to a patient’s somatic cells. Any modification and any effects are restricted only to that patient and are not inherited by future generations.

Detailed explanation-3: -Somatic cell gene therapy transfer or express human genes into a patient target cells (except cells that do not give rise to the eggs and sperm). This technique aims to treat a disorder only in the diseased person, not in their descendants.

Detailed explanation-4: -Somatic cell gene therapy is accepted to treat many disorders such as muscular dystrophy, cancer, cystic fibrosis, certain infectious diseases, etc. A single gene disorder like haemophilia, thalassaemia, cystic fibrosis, etc. have good chances of being cured by somatic cell gene therapy.

Detailed explanation-5: -Somatic gene therapy pinpoints on the improvement of genetic disease by handling of nonreproductive or somatic tissues. This method of gene therapy includes the exclusion of some of the dysfunctional cells and introducing them with a cloned wild-type gene.