PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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All sons will also have the disorder
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All daughters will be carriers of the disorder
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Half the sons and half the daughters will be carriers of the disorder
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None of the sons will have the disorder, but half of the daughters will be carriers
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Detailed explanation-1: -Most sex-linked disorders are carried on the X chromosome, but a few are carried on the Y chromosome. Which of the following would ALWAYS be true about offspring born to a man having Y-linked disorder? In humans, red-green color blindness (Xb) is recessive, and normal color vision (XB) is dominant.
Detailed explanation-2: -Examples of X-linked recessive conditions include red-green color blindness and hemophilia A: Red-green color blindness. Red-green color blindness simply means that a person cannot distinguish shades of red and green (usually blue-green). Their visual acuity (ability to see) is normal.
Detailed explanation-3: -Sex-linked genes are located on either the X or Y chromosome, though it more commonly refers to genes located on the X-chromosome. For that reason, the genetics of sex-linked (or X-linked) diseases, disorders due to mutations in genes on the X-chromosome, results in a phenotype usually only seen in males.