PATHOLOGY

Detailed explanation-1: -X-linked recessive diseases most often occur in males. Males have only one X chromosome. A single recessive gene on that X chromosome will cause the disease. The Y chromosome is the other half of the XY gene pair in the male.

Detailed explanation-2: -X-linked recessive conditions most often occur in males. X-linked recessive inheritance is a way a genetic trait or condition can be passed down from parent to child through mutations (changes) in a gene on the X chromosome.

Detailed explanation-3: -Sex-linked traits that are controlled by recessive alleles are more likely to show up in males. A doctor can look at the chromosomes of a cell in a karyotype.

Detailed explanation-4: -Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females.

Detailed explanation-5: -Males are affected more often than females, because the gene is located on the X chromosome.