PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The first commercial application of genetic engineering was the use of bacteria to make insulin, a medicine needed by diabetics. Before the use of genetically-engineered bacteria, insulin had to be harvested from the pancreases of slaughtered animals.How has genetic engineering most likely improved the lives of diabetics?
A
It has made the demand for insulin decrease.
B
It has made the incidence of diabetes decrease.
C
It has made it easier for diabetics to inject themselves with insulin.
D
It has made insulin cheaper and more readily available.
Explanation: 

Detailed explanation-1: -In the early 1900s, insulin for diabetes patients was extracted from slaughtered cows and pigs. However, in the 1970s, genetic engineering technology allowed scientists to engineer a bacterium to produce human insulin. There are no benefits to this form of biotechnology.

Detailed explanation-2: -1982: FDA approves the first consumer GMO product developed through genetic engineering: human insulin to treat diabetes. 1986: The federal government establishes the Coordinated Framework for the Regulation of Biotechnology.

Detailed explanation-3: -The genetic engineering process The gene for human insulin is inserted into the gap in the plasmid. This plasmid is now genetically modified. The genetically modified plasmid is introduced into a new bacteria or yeast cell. This cell then divides rapidly and starts making insulin.

Detailed explanation-4: -The first genetically engineered, synthetic “human” insulin was produced in 1978 using E. coli bacteria to produce the insulin. Eli Lilly went on in 1982 to sell the first commercially available biosynthetic human insulin under the brand name Humulin.

Detailed explanation-5: -Hint: Human insulin can be produced by inserting the human insulin gene into the plasmid, putting the plasmid into bacteria, and putting the “recombinant” bacteria in fermentation tanks. There, the bacteria begin producing human insulin.

There is 1 question to complete.