PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Not the result of a genetic disorder.
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Both parents carry the recessive gene.
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CF is a chromosomal mutation and not related to parental genotypes.
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CF is caused by a mutation in pair 21.
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Detailed explanation-1: -The gene that causes cystic fibrosis is recessive. This means that in order to have cystic fibrosis, children must inherit two copies of the gene, one from each parent.
Detailed explanation-2: -If both parents, are carriers for CF, a future child could get two mutations, (C) one from each parent and therefore have cystic fibrosis. When both parents are carriers (CN), every baby has 25% chance of having cystic fibrosis.
Detailed explanation-3: -A child can inherit CF only if both parents carry a CF gene (that is, each parent either has CF or is a carrier*) and both parents pass the CF gene on to their child.
Detailed explanation-4: -A child will be born with CF only if they inherit one CF gene from each parent. A person who has only one CF gene is called a CF carrier. They are healthy and don’t have the disease. But they are a carrier of the disease.