PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Until recently, looking through detailed records on family history of disease was the only way to try to avoid certain genetic conditions in some purebred dogs, such as a bleeding disorder called von Willebrand’s Disease. What technological advances may have reduced the need for this process?
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Determination of the sequence of the human genome
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Development of canine testing for genetic disease carriers
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None of these
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Use of reproductive sperm donation to increase fertility
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Explanation:
Detailed explanation-1: -Causes. Most people who have VWD are born with it. It almost always is inherited, or passed down, from a parent to a child. VWD can be passed down from either the mother or the father, or both, to the child.
Detailed explanation-2: -Autosomal dominant VWD is caused by changes in only one copy of the gene related to the disorder. In autosomal dominant inheritance, a child will inherit the bleeding disorder if he or she gets a VWD allele (the form of the gene that has a genetic change causing VWD) from one parent who has the disorder.
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