PATHOLOGY

Detailed explanation-1: -Cystic fibrosis. Sickle cell disease. Tay-Sachs disease. 21-May-2022

Detailed explanation-2: -Examples of autosomal recessive disorders include cystic fibrosis, sickle cell anemia, and Tay-Sachs disease.

Detailed explanation-3: -Cystic fibrosis is an autosomal recessive disorder, meaning that is not inherited solely from the mother or father as in sex-linked disorders. Rather, cystic fibrosis is inherited when an individual receives a mutated copy of the gene associated with cystic fibrosis from both parents.

Detailed explanation-4: -Autosomal recessive is one of several ways that a trait, disorder, or disease can be passed down through families. An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop.

Detailed explanation-5: -Cystic fibrosis is the most common, lethal, inherited disease in white populations. Approximately 1 in 2500 newborns in the United States is born with the disease. It typically displays autosomal recessive inheritance requiring each parent to provide a pathogenic allele to their child for the disease to manifest.