PATHOLOGY

Detailed explanation-1: -People with one copy of a recessive disease gene are called carriers. Carriers usually don’t have symptoms of the disease. But, the gene can often be found by sensitive laboratory tests. In autosomal recessive inheritance, the parents of an affected individual may not show the disease (they are carriers).

Detailed explanation-2: -An individual who carries one harmful allele for an autosomal recessive disorder is known as a carrier. And an organism is said to be heterozygous if it possesses two distinct alleles of a gene. Carriers are heterozygous because they have two alleles of a gene.

Detailed explanation-3: -Autosomal Recessive Inheritance Each parent of an affected patient is typically a heterozygous carrier, and has one normal and one abnormal copy of the gene (Figure 3.1B).

Detailed explanation-4: -Recessive inheritance means both genes in a pair must be abnormal to cause disease. People with only one defective gene in the pair are called carriers. These people are most often not affected with the condition. However, they can pass the abnormal gene to their children.

Detailed explanation-5: -Answer and Explanation: Heterozygous individuals are often called carriers of a trait because they have one dominant allele and one recessive allele that is hidden, so they carry it without it showing up.