PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is meant by the term multiple alleles?
A
more than two genes that control a trait
B
three or more forms of a gene that code for a single trait
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -However, in the given population, there are instances wherein there are more than two alternatives (alleles) existing. Those instances are referred to as “multiple allelism” where different forms of the same gene exist within the population. These three or more variants for the same gene are called multiple alleles.

Detailed explanation-2: -Multiple alleles of a gene occupy the same locus on the chromosome. Multiple alleles are the alternative forms of the same gene so they influence the same trait. The wild-type allele is mostly dominant over the mutant alleles. The wild type is considered the standard and all other alleles are considered variants.

Detailed explanation-3: -The majority of human genes are thought to have more than two normal versions or alleles. Traits controlled by a single gene with more than two alleles are called multiple allele traits. An example is ABO blood type. Your blood type refers to which of certain proteins called antigens are found on your red blood cells.

Detailed explanation-4: -Multi-allele traits have more than two alleles at a population level, although individuals still only get one from each parent. These alleles may exhibit classic dominance, they may mask each other, they may add to or subtract from each other, or some combination of these effects.

Detailed explanation-5: -Three or more alleles of the same gene that code for a single trait called multiple allele traits. These traits are more common in humans than single allele traits as the basis for many physical features are due to complex genetic mechanisms.

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