PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the percentage risk of a child inheriting Huntington’s disease of only one parent has the disease?
A
0%
B
25%
C
50%
D
100%
Explanation: 

Detailed explanation-1: -Each child of a parent with HD has a 50 percent chance of inheriting the HD gene. A child who does not inherit the HD gene will not develop the disease, and generally, they cannot pass it on to their children or other future generations.

Detailed explanation-2: -With dominant diseases like Huntington’s Disease (HD), it is usually pretty easy to figure out risks. Generally if one parent has it then each child has a 50% chance of having it too. And if neither parent has the disease, then odds are that none of the kids will either. Huntington’s is a dominant genetic disease.

Detailed explanation-3: -Each child born to either a mother or father with Huntington’s disease has a 50 percent risk of having the disease.

Detailed explanation-4: -Juvenile Huntington’s occurs in approximately 16% of all cases. Huntington’s disease is not prevalent within any particular population. All races and ethnic groups, and both sexes are affected.

Detailed explanation-5: -Huntington’s disease is autosomal dominant, meaning inheritance of just a single copy of an abnormal chromosome from a biological parent is enough to cause it. If one parent carries the abnormal gene, each of their biological children has a 50 percent chance of Huntington’s disease inheritance.

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