PATHOLOGY

Detailed explanation-1: -Cystic fibrosis (CF) is a disease that is passed down through families. It is caused by a defective gene that makes the body produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas.

Detailed explanation-2: -Cystic fibrosis is an example of a recessive disease. That means a person must have a mutation in both copies of the CFTR gene to have CF.

Detailed explanation-3: -Cystic fibrosis is an inherited condition that causes sticky mucus to build up in the lungs and digestive system.

Detailed explanation-4: -CF causes thick mucus to build up and clog certain parts of the body such as the lung. The buildup is caused by an abnormal gene called CFTR (cystic fibrosis transmembrane regulator). CFTR controls the flow of water and salt in and out of the body’s cells. Changes cause mucus to become thickened and sticky.

Detailed explanation-5: -Cystic fibrosis is a genetic disease. People with CF have inherited two copies of the defective CF gene-one copy from each parent. Both parents must have at least one copy of the defective gene. People with only one copy of the defective CF gene are called carriers, but they do not have the disease.