PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Chromosomes (pairs 1-22) are arranged by size
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Sex chromosomes are found at the end
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A normal karyotype has 46 chromosomes or 23 pairs
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Having missing or extra chromosomes does not indicate a disorder
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Detailed explanation-1: -Answer and Explanation: The statement (b) All eukaryotic karyotypes contain 46 chromosomes is not true.
Detailed explanation-2: -A karyotype test checks the chromosomes in your cells to: See whether you have a full set of 46 chromosomes. Having too many or too few chromosomes can cause serious problems with health, growth, and normal development, such as Down syndrome (extra chromosome 21) and Turner syndrome (missing X chromosome).
Detailed explanation-3: -Chromosomal abnormalities can also cause miscarriage, disease, or problems in growth or development. The most common type of chromosomal abnormality is known as aneuploidy, an abnormal chromosome number due to an extra or missing chromosome.
Detailed explanation-4: -Diseases such as anemia, leukemia, lymphoma or multiple myeloma can change your chromosomes. Finding these abnormalities with karyotyping can guide your treatment.